Why is this medication prescribed?As Obesity becomes normal in modern life,Fat loss Lorcaserin was producrd. Lorcaserin,like Orlistat,got the Approval of FDA in 1999,was used to help adults who are obese or who are overweight and have weight-related medical problems to lose weight and keep from gaining back that weight. Lorcaserin is in a class of medications called serotonin receptor agonists.Lorcaserin must be used along with a reduced calorie diet and an exercise plan.Lorcaserin HCL
What is Lorcaserin raw powder?
Lorcaserin raw ,the raw material of drug Lorcaserin,is a kind of White to off-white powder,many fat loss products supplier usually buy high purity Lorcaserin raw powder,then make it into finished one,the detail of Lorcaserin powder as below:
CAS:616202-92-7,
Molecular Formula: C11H14ClN
Molecular Weight: 195.692
Melt Point: 212°C
Storage Temp: RT
Lorcaserin generic and brand name
The drug is available under generic name Lorcaserin and brand name Belviq.
Lorcaserin is developed by pharmaceutical company Arena Pharmaceuticals.
Lorcaserin is manufactured by Arena Pharmaceuticals and marketed by Eisai Pharmaceuticals.
How does Lorcaserin/Belviq work?
Mechanism of action
The drug works by controlling appetite — specifically by activating brain receptors for serotonin, a neurotransmitter that triggers feelings of satiety and satisfaction. Intake of food is controlled by satiety center, located in ventromedial nucleus of hypothalamus and hunger center present in lateral hypothalamus.Various inputs from higher centers and gastrointestinal tracts converge in arcuate nucleus, where two types of neurons controlling food intake is present. Firstly, food intake stimulatory group producing agouti-related protein and neuropeptide Y; and secondly, food intake inhibitory group containing cocaine and amphetamine regulated transcript (CART) and pro-opiomelanocortin (POMC) neurons. POMC contains 5-HT 2C receptors, which when activated releases alpha-melanocyte-stimulating hormone (alfa-MSH).Both inhibitory and stimulatory neurons further projects paraventricular nucleus in the hypothalamus.Paraventricular nucleus contains melanocyte 4 receptors (MC4R) that inhibits appetiteIn therapeutic doses lorcaserin acts as a selective 5-HT 2C agonist on POMC neurons, which in turn causes release of alfa MSH. Further alfa MSH acts on MC4R in paraventricular nucleus in the hypothalamus, leading to decrease in appetite. In supratherapeutic doses, lorcaserin also acts on 5-HT 2B and 5-HT 2A receptors.